Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6) (AA 501-582) Antikörper (PerCP)

Produktnummer ABIN2483747

Dieses Anti--Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von in WB, IHC, IF und ICC. Geeignet für Ratte.

Kurzübersicht für Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6) (AA 501-582) Antikörper (PerCP) (ABIN2483747)

Target: Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6)

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: PerCP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: S29-29

Produktdetails

Bindungsspezifität: AA 501-582

Spezifität: Detects ~60 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Fusion protein amino acids 501-582 (cytoplasmic C-terminus) of rat VGlut2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN2483747 was sufficient for detection of VGLut2 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Antigendetails

Target: Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6)

Andere Bezeichnung: VGLUT2

Hintergrund: The ATP-dependent, chloride-sensitive vesicular glutamate transporters (VGLUT) include BNPI (VGLUT1), VGLUT2 (DNPI) and VGLUT3. The brain expresses BNPI (brain specific Na+-dependent inorganic phosphate (Pi) cotransporter) and VGLUT2 in a complementary fashion. The telencephalic regions express BNPI, whereas the lower brainstem and diencephalic regions express VLGUT2. Rat pinealocytes express both BNPI and VGLUT2. The striatum, hippocampus, cerebral cortex and raphe nuclei express VGLUT3 in a small number of neurons. Pancreatic α and β cells express BNPI and VGLUT2 in response to glucose concentrations. Human VGLUT3 shares a 72 % sequence homology with VLGUT2 and BNPI.

Gen-ID: 84487

NCBI Accession: NP_445879

UniProt: Q9JI12