SLC38A1 Antikörper (AA 1-63) (PE)

Produktnummer ABIN2482524

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SLC38A1 in WB, IHC, ICC und IF. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für SLC38A1 Antikörper (AA 1-63) (PE) (ABIN2482524)

Target: SLC38A1 (Solute Carrier Family 38 Member 1 (SLC38A1))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SLC38A1 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: S104-32

Produktdetails anti-SLC38A1 Antikörper (PE)

Bindungsspezifität: AA 1-63

Spezifität: Detects ~50 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Fusion protein amino acids 1- 63 of rat SNAT1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN2482524 was sufficient for detection of SNAT1 in 20 μg of lysates from neocortical neurons cultured under amino acid starvation conditions and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu SLC38A1

Target: SLC38A1 (Solute Carrier Family 38 Member 1 (SLC38A1))

Andere Bezeichnung: SLC38A1

Hintergrund: The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. The SNAT1 protein, also designated ATA1 or NAT2 is encoded by the human gene SLC38A1 which maps to chromosome 12q13.11. SNAT1 is responsible for the transport of glutamine, an intermediate in the synthesis of urea, and may be involved in the generation of glutamate in the retina. SNAT1 protein may be detected in some tissues such as heart, brain and placenta and expression levels are enriched in certain neuronal populations within the CNS. SNAT1 is not present in astrocytes.

Gen-ID: 170567

NCBI Accession: NP_620187

UniProt: Q9JM15