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Neisseria Meningitidis Antikörper

Reaktivität: Neisseria meningitidis IF, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2475826
  • Target Alle Neisseria Meningitidis Produkte
    Neisseria Meningitidis
    Reaktivität
    • 16
    • 4
    Neisseria meningitidis
    Wirt
    • 20
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 8
    • 4
    • 4
    • 3
    • 1
    Dieser Neisseria Meningitidis Antikörper ist unkonjugiert
    Applikation
    • 12
    • 11
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), ELISA
    Spezifität
    This antibody reacts with Neisseria meningitidis serogroups A, B and C and is thought to recognize all antigens. Other serogroups have not been tested. N. meningitidis is a gram-negative bacteria that is the causative agent of meningitis. There are 13 known significant serogroups that are classified according to the structure of their polysaccharide capsule. Serogroups, A, B, C, D, X, Y, Z, 29E and W135 are responsible for virtually all cases of the human disease. The carbohydrate component of the capsular membrane induces a T cell independent immune response, so neither long term immunity by memory cell formation nor antibody affinity maturation is observed. Rather than being engulfed and processed by an antigen presenting cell, the carbohydrate capsule interacts directly with B cells. This interaction causes production of serogroup specific antibodies, primarily IgM. IgG is also produced with an IgG1 response predominating in children and an IgG2 response predominating in adults.
    Produktmerkmale
    Purified IgG
    Aufreinigung
    Purified
    Immunogen
    Whole cell preparation of N. meningitidis types A, B and C
    Isotyp
    IgG
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    4 mg/mL
  • Target
    Neisseria Meningitidis
    Abstract
    Neisseria Meningitidis Produkte
    Substanzklasse
    Bacteria
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