Cholera Toxin beta Antikörper

Produktnummer ABIN2472974

Produktdetails anti-Cholera Toxin beta Antikörper

Target: Cholera Toxin beta

Reaktivität: Vibrio cholerae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cholera Toxin beta Antikörper ist unkonjugiert

Applikation: ELISA, Immunodiffusion (ID)

Verwendungszweck: Rabbit anti cholera toxin beta antibody recognizes the beta subunit of cholera toxin.

Produktmerkmale: Purified Ig

Aufreinigung: Purified

Immunogen: Purified choleragenoid

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 4.0 mg/mL

Buffer: Phosphate buffered saline, 0.1% Sodium Azide (NaN3)

Handhabung: This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended.

Haltbarkeit: 18 months

Referenzen für anti-Cholera Toxin beta Antikörper (ABIN2472974)

Thangawng, Kim, Golden, Anderson, Robertson, Low, Ligler: "A hard microflow cytometer using groove-generated sheath flow for multiplexed bead and cell assays." in: Analytical and bioanalytical chemistry, Vol. 398, Issue 5, pp. 1871-81, (2010) (PubMed).

Details zu Cholera Toxin beta

Target: Cholera Toxin beta

Abstract: Cholera Toxin beta Produkte

Hintergrund: The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

UniProt: P01556