PTH1R Antikörper (pThr1)

Produktnummer ABIN2470513

Dieser Maus Monoklonal Antikörper detektiert spezifisch PTH1R in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh), Schwein, Hund, Affe, Pferd, Gibbon, Gorilla und Orang-Utan.

Kurzübersicht für PTH1R Antikörper (pThr1) (ABIN2470513)

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Reaktivität: Human, Rind (Kuh), Schwein, Hund, Affe, Pferd, Gibbon, Gorilla, Orang-Utan

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTH1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PTH1R Antikörper

Bindungsspezifität: pThr1

Spezifität: Recognizes human PTH/PTHrP receptor, Mr 80kD, and the receptor dimer, Mr 160kD. A faint nonspecific band at 110kD is also detected. This antibody does not detect the PTH2 receptor.

Aufreinigung: Protein G Column

Immunogen: PTHR1 monoclonal antibody was raised against a synthetic peptide corresponding to aa 146 - 169 of PTHR1 (Human).

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: PTHR1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 15 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.6, 0.07 % sodium azide, 30 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Product should be stored long term (months) at -20 °C and short term (weeks) at 4 °C.

Details zu PTH1R

Target: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Andere Bezeichnung: PTHR1

Hintergrund: PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR.

Gen-ID: 5745

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process