MYL9 Antikörper (C-Term)

Produktnummer ABIN2470242

Dieses Anti-MYL9-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MYL9 in WB, ELISA, IHC und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für MYL9 Antikörper (C-Term) (ABIN2470242)

Target: MYL9 (Myosin Regulatory Light Polypeptide 9 (MYL9))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYL9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-MYL9 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Immunoaffinity Chromatography

Immunogen: MYL9 antibody was raised against amino acids 12-27 from the C-Terminus of human myosin light chain protein.

Anwendungsinformationen

Applikationshinweise: MYL9 antibody can be used in immunohistochemistry starting at 2.5 - 5 μg/mL, and flow cytometry.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store MYL9 antibody at 4 °C or -20 °C.

Details zu MYL9

Target: MYL9 (Myosin Regulatory Light Polypeptide 9 (MYL9))

Andere Bezeichnung: MYL9

Hintergrund: Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains each ~200,000 daltons, and four light chains each ~16,000 - 21,000 daltons. Activation of smooth and cardiac muscle primarily involves pathways that increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. The selected peptide sequence used to generate the polyclonal antibody is located near the amino terminal end of the polypeptide corresponding to the smooth/non-muscle form of myosin regulatory light chain found in cardiac myocytes in addition to smooth and non-muscle cells. This sequence differs from that of the sarcomeric/ cardiac form of myosin regulatory light chain that has a different sequence around the phosphorylation site. Human, mouse and rat have almost identical sequences.

Gen-ID: 10398

UniProt: P24844