TMEM123 Antikörper (AA 173-188)

Produktnummer ABIN2470150

Produktdetails anti-TMEM123 Antikörper

Target: TMEM123 (Transmembrane Protein 123 (TMEM123))

Bindungsspezifität: AA 173-188

Reaktivität: Human, Affe, Kaninchen, Gibbon, Gorilla

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM123 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Protein G Column

Immunogen: TMEM123 antibody was raised against amino acids 173 - 188 of TMEM123 (Human).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TMEM123 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: TMEM123 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.

Details zu TMEM123

Target: TMEM123 (Transmembrane Protein 123 (TMEM123))

Andere Bezeichnung: TMEM123 (TMEM123 Produkte)

Synonyme: KCT3 antikoerper, PORIMIN antikoerper, PORMIN antikoerper, 2310075C12Rik antikoerper, RGD1305625 antikoerper, kct3 antikoerper, pormin antikoerper, porimin antikoerper, transmembrane protein 123 antikoerper, transmembrane protein 123 L homeolog antikoerper, TMEM123 antikoerper, Tmem123 antikoerper, tmem123.L antikoerper, tmem123 antikoerper

Hintergrund: Porimin was identified by a monoclonal antibody developed by immunizing mice with apoptotic cells. One of these antibodies, designated anti-Porimin (for pro-oncosis receptor inducing membrane injury), was found to directly induce a unique type of cell death in Jurkat cells by binding to a 110- kDa cell surface receptor on Jurkat cells. Anti-Porimin-mediated cell death was preceded by cell aggregation, formation of plasma membrane pores, and the appearance of membrane blebs. More important, these cells show neither DNA fragmentation nor apoptotic bodies, but display lethal damage of the cell membrane.

Gen-ID: 114908

UniProt: Q8N131

Pathways: Regulation of Cell Size