TLX1 Antikörper (AA 300-330)

Produktnummer ABIN2470149

Dieses Anti-TLX1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TLX1 in WB und IHC. Geeignet für Maus, Human, Ratte, Rind (Kuh), Hund, Kaninchen, Fledermaus, Affe, Huhn, Pferd, Hamster, Gibbon und Gorilla.

Kurzübersicht für TLX1 Antikörper (AA 300-330) (ABIN2470149)

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Reaktivität: Maus, Human, Ratte, Rind (Kuh), Hund, Kaninchen, Fledermaus, Affe, Huhn, Pferd, Hamster, Gibbon, Gorilla

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TLX1 Antikörper

Bindungsspezifität: AA 300-330

Aufreinigung: Protein G Column

Immunogen: TLX1 antibody was raised against amino acids 300 - 330 of TLX1 (Human).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TLX1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: TLX1 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.

Details zu TLX1

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Andere Bezeichnung: TLX1

Hintergrund: HOX11, also called homeobox11 or Tcl-3 is located at the 10q24 T-Cell translocation breakpoint region. It encodes a homeobox-domain containing protein, HOX11, containing a glycine and proline-rich amino terminus. HOX11 is required for maintenance of the developing spleen and cell survival. The HOX11protein binds to a specific DNA sequence and localizes to the cell nucleus. It transactivates transcription of a reporter gene linked to a cis-regulatory element, acting as a positive transcription activator. The HOX11 gene is highly expressed in T-ALLs as a result of a t (7:10) (q35,q24) or t(10:14)(q24,qll) translocation. The homeobox gene is deregulated upon translocation into the T-cell receptor locus and activates a specific subset of tumor-associated target genes. HOX 11 gene translocation has been attributed to T-cell leukemia and lymphoid neoplasias.

Gen-ID: 3195

UniProt: P31314