SIRT7 Antikörper (AA 35-51)

Produktnummer ABIN2470139

Der Kaninchen Polyklonal Anti-SIRT7-Antikörper wurde für WB und IHC validiert. Er ist geeignet, SIRT7 in Proben von Human zu detektieren.

Kurzübersicht für SIRT7 Antikörper (AA 35-51) (ABIN2470139)

Target: SIRT7 (Sirtuin 7 (SIRT7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SIRT7 Antikörper

Bindungsspezifität: AA 35-51

Aufreinigung: Protein G Column

Immunogen: SIRT7 antibody was raised against amino acids 35 - 51 of SIRT7 (Human).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SIRT7 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 2.5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Product should be stored long term (months) at -20 °C and short term (weeks) at 4 °C.

Details zu SIRT7

Target: SIRT7 (Sirtuin 7 (SIRT7))

Andere Bezeichnung: SIRT7

Hintergrund: SIRT7 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.

Gen-ID: 51547

UniProt: Q9NRC8