CXCR4 Antikörper

Produktnummer ABIN2470068

Der Maus Monoklonal anti-CXCR4 Antikörper (Klon 12G5) (ABIN2470068) detektiert spezifisch CXCR4 in IHC, FACS und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Affe, Pavian und Schimpanse.

Kurzübersicht für CXCR4 Antikörper (ABIN2470068)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reaktivität: Human, Affe, Pavian, Schimpanse

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CXCR4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: 12G5

Produktdetails anti-CXCR4 Antikörper

Aufreinigung: Affinity Chromatography

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: CXCR4 antibody can be used in immunohistochemistry starting at 10 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.2, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze thaw cycles

Lagerung: 4 °C

Informationen zur Lagerung: Store CXCR4 antibody at 4 °C, Avoid Freezing

Details zu CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Andere Bezeichnung: CXCR4

Hintergrund: CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.

Gen-ID: 7852

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events