CXCR4 Antikörper
Kurzübersicht für CXCR4 Antikörper (ABIN2470068)
Target
Alle CXCR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Affinity Chromatography
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Isotyp
- IgG2a
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Applikationshinweise
- CXCR4 antibody can be used in immunohistochemistry starting at 10 μg/mL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.2, 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze thaw cycles
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store CXCR4 antibody at 4 °C, Avoid Freezing
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Andere Bezeichnung
- CXCR4
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Hintergrund
- CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.
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Gen-ID
- 7852
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UniProt
- P61073
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Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
Target
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