CXCR4 Antikörper
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- Target Alle CXCR4 Antikörper anzeigen
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Reaktivität
- Human, Affe, Pavian, Schimpanse
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CXCR4 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- Aufreinigung
- Affinity Chromatography
- Klon
- 12G5
- Isotyp
- IgG2a
- Top Product
- Discover our top product CXCR4 Primärantikörper
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- Applikationshinweise
- CXCR4 antibody can be used in immunohistochemistry starting at 10 μg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.2, 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze thaw cycles
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store CXCR4 antibody at 4 °C, Avoid Freezing
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- Target
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Andere Bezeichnung
- CXCR4 (CXCR4 Produkte)
- Hintergrund
- CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.
- Gen-ID
- 7852
- UniProt
- P61073
- Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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