CERK
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
Ceramide Kinase antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
As with all antibodies avoid freeze/thaw cycles.
Lagerung
4 °C/-80 °C
Informationen zur Lagerung
Ceramide Kinase antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Target
CERK
(Ceramide Kinase (CERK))
Andere Bezeichnung
Ceramide Kinase
Hintergrund
CERK, which phosphorylates Cer to produce ceramide 1-phosphate (C1P), was initially described as a Ca2+-stimulated lipid kinase that copurified with brain synaptic vesicles. CERK activity has been reported in HL60 cells, mast cells, and neutrophils. CERK is involved in phagolysosome formation in polymorphonuclear leukocytes and also in liposome fusion. C1P has been reported to have mitogenic effects. More recently, C1P was found to induce arachidonic acid release and prostanoid synthesis.