XCR1 antibody can be used in immunohistochemistry starting at 5 μg/mL, and immunofluorescence.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
As with all antibodies avoid freeze/thaw cycles.
Lagerung
4 °C/-80 °C
Informationen zur Lagerung
XCR1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Target
XCR1
(Chemokine (C Motif) Receptor 1 (XCR1))
Andere Bezeichnung
XCR1
Hintergrund
CCXCR1 is a Chemokine Receptor expressed in lymphotactin-responsive leukocyte cells. The viral macrophage inflammatory protein-II, vMIP-II (but not vMIP-I), has been found to be an antagonist of lymphotactin activity at CCXCR1. The CCXCR1 gene is located near the genes for C-C chemokine receptor 9 and SIV/HIV receptor Bonzo on chromosome 3. CCXCR1 is associated with inflammatory and immunological responses by regulating the trafficking of T and B lymphocytes and neutrophils. The up-regulation of CCXCR1 in peripheral T cells is correlated with the inflammatory process observed in Crohns disease.