SH3GL1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB37000
unconjugated
Applikationshinweise
SH3-containing Grb-2-like 1 protein antibody can be used for the detection of SH3-containing Grb-2-like 1 protein by Western Blot.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Konservierungsmittel
Without preservative
Handhabung
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
SH3GL1 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
Target
SH3GL1
(SH3-Domain GRB2-Like 1 (SH3GL1))
Andere Bezeichnung
SH3GL1
Hintergrund
SH3GL1 may play a regulatory role in synaptic vesicle recycling. It interacts with SYNJ1 and DNM1 through its SH3 domain with the proline-rich region of mixed lineage Leukemia (MLL) in either the fusion or the normal MLL protein. This protein is located in cytoplasmic, and peripheral membrane protein associated with internal membranes. Concentrated in presynaptic nerve terminals in neurons (By similarity). It s expressed ubiquitously. Higher expression in pancreas, placenta, prostate, testis and uterus. In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.