PPFIA1
Reaktivität: Human, Maus
WB, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
PTPRF interacting protein alpha 1 isoform b variant antibody can be used for the detection of PTPRF interacting protein alpha 1 isoform b variant by Western Blot.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Konservierungsmittel
Without preservative
Handhabung
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
PPFIA1 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
Target
PPFIA1
(Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))
LIP.1 antikoerper, LIP1 antikoerper, LIPRIN antikoerper, C030014K08Rik antikoerper, C87158 antikoerper, PTPRF interacting protein alpha 1 antikoerper, protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 antikoerper, PPFIA1 antikoerper, Ppfia1 antikoerper
Hintergrund
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.