Adam23 Antikörper (AA 72-144)
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- Target Alle Adam23 Antikörper anzeigen
- Adam23 (ADAM Metallopeptidase Domain 23 (Adam23))
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Bindungsspezifität
- AA 72-144
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Reaktivität
- Human
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Wirt
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Huhn
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Klonalität
- Polyklonal
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Konjugat
- Dieser Adam23 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Immunoaffinity Purified
- Top Product
- Discover our top product Adam23 Primärantikörper
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- Applikationshinweise
- ADAM 23 antibody can be used for the detection of ADAM 23 by Western Blot.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate-Buffered Saline. No preservatives added.
- Konservierungsmittel
- Without preservative
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- ADAM23 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- Target
- Adam23 (ADAM Metallopeptidase Domain 23 (Adam23))
- Andere Bezeichnung
- ADAM23 (Adam23 Produkte)
- Synonyme
- AW046396 antikoerper, MDC3 antikoerper, MDC-3 antikoerper, ADAM metallopeptidase domain 23 antikoerper, a disintegrin and metallopeptidase domain 23 antikoerper, ADAM23 antikoerper, Adam23 antikoerper
- Hintergrund
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FUNCTION: May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.
SUBUNIT: Ligand for integrin alpha-V/γ,-3.
SIMILARITY: Contains 1 peptidase M12B domain.
SUBCELLULAR LOCATION: Membrane, single-pass type I membrane protein (Potential). Secreted protein. Isoform Gamma.
TISSUE SPECIFICITY: Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.
DEVELOPMENTAL STAGE: Highly expressed in the fetal brain.
DOMAIN:A conserved motif AVN[ED]CD within the disintegrin-like domain could be involved in the binding to the integrin receptor.
SUMMARY: This protein is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is highly expressed in the brain and may function as an integrin ligand in the brain. - Molekulargewicht
- 91.9 kDa (calculated)
- Gen-ID
- 8745
- NCBI Accession
- NP_003803
- UniProt
- O75077
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