CXCR4 Antikörper (AA 6-41)
Kurzübersicht für CXCR4 Antikörper (AA 6-41) (ABIN2467958)
Target
Alle CXCR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 6-41
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Aufreinigung
- Immunoaffinity Purified
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Applikationshinweise
- C-X-C chemokine receptor type 4 antibody can be used for the detection of C-X-C chemokine receptor type 4 by Western Blot.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline. No preservatives added.
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Konservierungsmittel
- Without preservative
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Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- CXCR4 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Andere Bezeichnung
- CXCR4
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Hintergrund
- FUNCTION: Receptor for the C-X-C chemokine SDF-1. Transduces a signal by increasing the intracellular calcium ions level. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodelling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a primary receptor for some HIV-2 isolates and as a coreceptor with CD4 for HIV-1 X4 viruses (lymphocyte-tropic HIV-1 viruses, also called syncytium-inducing (SI) strains). Promotes Env-mediated fusion of the virus.
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Molekulargewicht
- 39.7 kDa (calculated)
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Gen-ID
- 7852
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NCBI Accession
- NP_003458
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UniProt
- P61073
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Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
Target
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