CXCR4 Antikörper (AA 6-41)

Produktnummer ABIN2467958

Der Huhn Polyklonal Anti-CXCR4-Antikörper wurde für WB validiert. Er ist geeignet, CXCR4 in Proben von Human, Maus, Ratte und Rind (Kuh) zu detektieren.

Kurzübersicht für CXCR4 Antikörper (AA 6-41) (ABIN2467958)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser CXCR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CXCR4 Antikörper

Bindungsspezifität: AA 6-41

Aufreinigung: Immunoaffinity Purified

Anwendungsinformationen

Applikationshinweise: C-X-C chemokine receptor type 4 antibody can be used for the detection of C-X-C chemokine receptor type 4 by Western Blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Konservierungsmittel: Without preservative

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: CXCR4 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Details zu CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Andere Bezeichnung: CXCR4

Hintergrund: FUNCTION: Receptor for the C-X-C chemokine SDF-1. Transduces a signal by increasing the intracellular calcium ions level. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodelling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a primary receptor for some HIV-2 isolates and as a coreceptor with CD4 for HIV-1 X4 viruses (lymphocyte-tropic HIV-1 viruses, also called syncytium-inducing (SI) strains). Promotes Env-mediated fusion of the virus.

Molekulargewicht: 39.7 kDa (calculated)

Gen-ID: 7852

NCBI Accession: NP_003458

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events