Verified
TFE3
Reaktivität: Human
WB, ELISA
Wirt: Ziege
Polyclonal
unconjugated
Applikationshinweise
Transcription factor E3 antibody can be used for the detection of Transcription factor E3 by Western Blot.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Konservierungsmittel
Without preservative
Handhabung
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
TFE3 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
Target
TFE3
(Transcription Factor E3 (TFE3))
Andere Bezeichnung
TFE3
Hintergrund
FUNCTION: Positive-acting transcription factor that binds to the immunoglobulin enchancer MUE3 motif. It binds also very well to a USF/MLTF site. Binding of TFE3 to DNA induces DNA binding.
DISEASE: Chromosomal aberrations involving TFE3 may be a cause of papillary renal cell carcinoma (PRCC). Translocation t(X,1)(p11.2,q21.2) with PRCC, translocation t(X,1)(p11.2,p34) with PSF, inversion inv(X)(p11.2,q12) that fuses NONO to TFE3.