TK1 Antikörper

Produktnummer ABIN2466869

Der Maus Monoklonal Anti-TK1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, TK1 in Proben von Human zu detektieren.

Kurzübersicht für TK1 Antikörper (ABIN2466869)

Target: TK1 (Thymidine Kinase 1, Soluble (TK1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 3B3-E11

Produktdetails anti-TK1 Antikörper

Aufreinigung: Protein G-purified

Immunogen: 5 -His-tagged recombinant human thymidine kinase.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C

Informationen zur Lagerung: Thymidine Kinase monoclonal antibody can be stored at 4 °C, stable for one year.

Details zu TK1

Target: TK1 (Thymidine Kinase 1, Soluble (TK1))

Andere Bezeichnung: Thymidine Kinase

Hintergrund: Thymidine kinase (TK) belongs to a group of enzymes such as dihydrofolate reductase, thymidylate synthase, and DNA polymerase that are involved in DNA synthesis and precursor production. High levels of these enzymes are present in proliferating cells, and low levels are found in resting cells, due to multiple regulatory mechanisms that ensure exclusive expression of these enzymes in replicating cells. TK is responsible for catalyzing the phosphorylation of thymidine, which functions as a part of the pyrimidine salvage pathway involved in DNA synthesis. The activities of enzymes such as TK are essential for the activation of several chemotherapeutically important nucleoside analogues that are administered as prodrugs.

Gen-ID: 3978

UniProt: P18858