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SNCA Antikörper (truncated)
SNCA
Reaktivität: Human
WB, ELISA, IHC
Wirt: Maus
Monoclonal
2B2D1-2B2A11
unconjugated
Produktnummer ABIN2464103
Produktdetails anti-SNCA Antikörper
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Target
Alle SNCA Antikörper anzeigen
SNCA
(Synuclein, alpha (SNCA))
Bindungsspezifität
Alle Epitope für SNCA Antikörper
truncated
Reaktivität
Alle Reaktivitäten für SNCA Antikörper
Human
Wirt
Alle Wirte für SNCA Antikörper
Maus
Klonalität
Alle Klonalitäten für SNCA Antikörper
Monoklonal
Konjugat
Alle Konjugate für SNCA Antikörper
Dieser SNCA Antikörper ist unkonjugiert
Applikation
Alle Applikationen für SNCA Antikörper
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Immunogen
Ni-NTA purified truncated recombinant SNCA expressed in E. Coli strain BL21 (DE3).
Klon
2B2D1-2B2A11
Top Product
Discover our top product SNCA Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Western Blot:1:500 - 1:2,000 IHC(P):1:500 - 1:2,000 IHC(F):1:500 - 1:2,000 ELISA:Propose dilution 1:10,000 Determining optimal working dilutions by titration test.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Lagerung
-20 °C
Informationen zur Lagerung
SNCA monoclonal antibody can be stored at -20 °C, stable for one year.
Details zu SNCA
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Target
SNCA
(Synuclein, alpha (SNCA))
Andere Bezeichnung
SNCA (SNCA Produkte )
Synonyme
snca antikoerper, MGC64356 antikoerper, LOC619283 antikoerper, NACP antikoerper, alphaSYN antikoerper, PARK1 antikoerper, PARK4 antikoerper, PD1 antikoerper, synuclein alpha L homeolog antikoerper, alpha-synuclein antikoerper, synuclein alpha antikoerper, synuclein, alpha antikoerper, snca.L antikoerper, LOC619283 antikoerper, SNCA antikoerper, Snca antikoerper
Hintergrund
Alpha-synuclein (SNCA), with 140-amino acid protein (about 15 kDa), belongs to the synuclein family, which also includes beta- and gamma-synuclein. SNCA is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). SNCA is implicated in the regulation of dopamine release and transport. The triplication of the SNCA can cause Parkinson disease (PD) and diffuse Lewy body disease within the same kindred. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Immunohistochemistry for SNCA has become the histological technique of choice for the diagnosis for Parkinson's disease, Dementia with Lewy bodies and Multiple System Atrophy.
Gen-ID
6622
UniProt
P37840
Pathways
Synaptic Membrane , Regulation of G-Protein Coupled Receptor Protein Signaling , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process , Platelet-derived growth Factor Receptor Signaling , Negative Regulation of Transporter Activity , Regulation of long-term Neuronal Synaptic Plasticity
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