PTK6 Antikörper (truncated)

Produktnummer ABIN2464095

Produktdetails anti-PTK6 Antikörper

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Bindungsspezifität: truncated

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTK6 Antikörper ist unkonjugiert

Applikation: ELISA

Immunogen: Ni-NTA purified truncated recombinant PTK6 expressed in E. Coli strain BL21 (DE3).

Klon: 2H12B8

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: -20 °C

Informationen zur Lagerung: PTK6 monoclonal antibody can be stored at -20 °C, stable for one year.

Details zu PTK6

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Andere Bezeichnung: PTK6 (PTK6 Produkte)

Synonyme: BRK antikoerper, Sik antikoerper, Tksk antikoerper, tks antikoerper, zgc:153964 antikoerper, protein tyrosine kinase 6 antikoerper, PTK6 protein tyrosine kinase 6 antikoerper, PTK6 protein tyrosine kinase 6b antikoerper, PTK6 antikoerper, Ptk6 antikoerper, ptk6b antikoerper

Hintergrund: PTK6 (protein tyrosine kinase 6, BRK or FLJ42088),with 451-amino acid protein (about 51 kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.

Gen-ID: 5753

UniProt: Q13882