GSTP1 Antikörper (truncated)

Produktnummer ABIN2464062

Der Maus Monoklonal anti-GSTP1 Antikörper (Klon 3F2C2) (ABIN2464062) detektiert spezifisch GSTP1 in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GSTP1 Antikörper (truncated) (ABIN2464062)

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GSTP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 3F2C2

Produktdetails anti-GSTP1 Antikörper

Bindungsspezifität: truncated

Immunogen: Ni-NTA purified truncated recombinant GSTP1 expressed in E. Coli strain BL21 (DE3).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: -20 °C

Informationen zur Lagerung: GSTP1 monoclonal antibody can be stored at -20 °C, stable for one year.

Details zu GSTP1

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Andere Bezeichnung: GSTP1

Hintergrund: GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90 % ) of prostate carcinomas and is associated with transcriptional down-regulation.

Gen-ID: 2950

UniProt: P09211

Pathways: Cellular Response to Molecule of Bacterial Origin