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BLK Antikörper (truncated)

BLK Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 9D10B7H6-9D10A8F8 unconjugated
Produktnummer ABIN2464018
  • Target Alle BLK Antikörper anzeigen
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    Bindungsspezifität
    • 15
    • 13
    • 9
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    truncated
    Reaktivität
    • 65
    • 23
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 53
    • 9
    • 1
    Maus
    Klonalität
    • 55
    • 10
    Monoklonal
    Konjugat
    • 34
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BLK Antikörper ist unkonjugiert
    Applikation
    • 51
    • 36
    • 27
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Immunogen
    Ni-NTA purified truncated recombinant BLK expressed in E. Coli strain BL21 (DE3).
    Klon
    9D10B7H6-9D10A8F8
    Isotyp
    IgG1
    Top Product
    Discover our top product BLK Primärantikörper
  • Applikationshinweise
    Western Blot:1:500 - 1:2,000
    IHC(P):1:500 - 1:2,000
    IHC(F):1:500 - 1:2,000
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    BLK monoclonal antibody can be stored at -20 °C, stable for one year.
  • Target
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    Andere Bezeichnung
    BLK (BLK Produkte)
    Synonyme
    bltk antikoerper, si:dkey-33i22.2 antikoerper, zgc:136231 antikoerper, MODY11 antikoerper, BLK proto-oncogene, Src family tyrosine kinase antikoerper, B lymphoid kinase antikoerper, blk antikoerper, BLK antikoerper, Blk antikoerper
    Hintergrund
    BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56 kDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.
    Gen-ID
    640
    UniProt
    P51451
    Pathways
    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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