SRF Antikörper
Kurzübersicht für SRF Antikörper (ABIN2463837)
Target
Alle SRF Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Aufreinigung
- Antibody is purified by protein A chromatography method.
-
Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SRF.
-
-
-
-
Applikationshinweise
- SRF antibody can be used for detection of SRF by ELISA at 1:1562500. SRF antibody can be used for detection of SRF by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
-
Konzentration
- 1 mg/mL
-
Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
-
Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SRF antibody at -20 °C.
-
-
- SRF (Serum Response Factor (SRF))
-
Andere Bezeichnung
- SRF
-
Hintergrund
- SRF is a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).
-
Molekulargewicht
- 52 kDa
-
Gen-ID
- 6722
-
NCBI Accession
- NP_003122
-
UniProt
- P11831
Target
-