Caveolin 3 Antikörper
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- Target Alle Caveolin 3 (CAV3) Antikörper anzeigen
- Caveolin 3 (CAV3)
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Reaktivität
- Human, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caveolin 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CAV3.
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- Discover our top product CAV3 Primärantikörper
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- Applikationshinweise
- CAV3 antibody can be used for detection of CAV3 by ELISA at 1:12500. CAV3 antibody can be used for detection of CAV3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store CAV3 antibody at -20 °C.
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- Target
- Caveolin 3 (CAV3)
- Andere Bezeichnung
- CAV3 (CAV3 Produkte)
- Hintergrund
- CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
- Molekulargewicht
- 17 kDa
- Gen-ID
- 859
- NCBI Accession
- NP_001225
- UniProt
- P56539
- Pathways
- Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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