TIAL1 Antikörper

Produktnummer ABIN2463661

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch TIAL1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Hund.

Kurzübersicht für TIAL1 Antikörper (ABIN2463661)

Target: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIAL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TIAL1 Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TIAL1.

Anwendungsinformationen

Applikationshinweise: TIAL1 antibody can be used for detection of TIAL1 by ELISA at 1:62500. TIAL1 antibody can be used for detection of TIAL1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TIAL1 antibody at -20 °C.

Details zu TIAL1

Target: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Andere Bezeichnung: TIAL1

Hintergrund: The protein encoded by TIAL1 is a member of a family of RNA-binding proteins and possesses nucleolytic activity against cytotoxic lymphocyte target cells. The gene product is a cytotoxic granule-associated protein and has been shown to bind specifically to poly (A) homopolymers and to fragment DNA in permeabilized target cells. It has been suggested that members of this protein family may be involved in the induction of apoptosis. One isoform contains a lysosome-targeting motif in its C-terminal auxiliary domain, however, alternative splicing results in a T-cluster DNA-binding isoform, differing at the C-terminus where a hydrophobic sequence replaces the lysosome-targeting motif.

Molekulargewicht: 42 kDa

Gen-ID: 7073

NCBI Accession: NP_003243

UniProt: Q01085