PHF6 Antikörper

Produktnummer ABIN2463418

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PHF6 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Hund.

Kurzübersicht für PHF6 Antikörper (ABIN2463418)

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PHF6 Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PHF6.

Anwendungsinformationen

Applikationshinweise: PHF6 antibody can be used for detection of PHF6 by ELISA at 1:312500. PHF6 antibody can be used for detection of PHF6 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PHF6 antibody at -20 °C.

Details zu PHF6

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Andere Bezeichnung: PHF6

Hintergrund: PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. PHF6 is a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of its gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS).This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molekulargewicht: 35 kDa, 41 kDa, 41 kDa

Gen-ID: 84295

NCBI Accession: NP_115711

UniProt: Q8IWS0