ST14 Antikörper

Produktnummer ABIN2463128

Der Kaninchen Polyklonal Anti-ST14-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, ST14 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ST14 Antikörper (ABIN2463128)

Target: ST14 (Suppression of Tumorigenicity 14 (ST14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ST14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-ST14 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ST14.

Anwendungsinformationen

Applikationshinweise: ST14 antibody can be used for detection of ST14 by ELISA at 1:312500. ST14 antibody can be used for detection of ST14 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ST14 antibody at -20 °C.

Details zu ST14

Target: ST14 (Suppression of Tumorigenicity 14 (ST14))

Andere Bezeichnung: ST14

Hintergrund: ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

Molekulargewicht: 46 kDa

Gen-ID: 6768

UniProt: Q8WVC1