SEC63 Antikörper
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- Target Alle SEC63 Antikörper anzeigen
- SEC63 (SEC63 Homolog (SEC63))
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Reaktivität
- Human, Maus, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SEC63 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SEC63.
- Top Product
- Discover our top product SEC63 Primärantikörper
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- Applikationshinweise
- SEC63 antibody can be used for detection of SEC63 by ELISA at 1:62500. SEC63 antibody can be used for detection of SEC63 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SEC63 antibody at -20 °C.
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- Target
- SEC63 (SEC63 Homolog (SEC63))
- Andere Bezeichnung
- SEC63 (SEC63 Produkte)
- Synonyme
- DNAJC23 antikoerper, ERdj2 antikoerper, PRO2507 antikoerper, SEC63L antikoerper, 5730478J10Rik antikoerper, AI649014 antikoerper, AW319215 antikoerper, SEC63-like antikoerper, zgc:92718 antikoerper, SEC63 homolog, protein translocation regulator antikoerper, SEC63-like (S. cerevisiae) antikoerper, SEC63 homolog, protein translocation regulator L homeolog antikoerper, SEC63 antikoerper, Sec63 antikoerper, sec63 antikoerper, sec63.L antikoerper
- Hintergrund
- The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
- Molekulargewicht
- 88 kDa
- Gen-ID
- 11231
- NCBI Accession
- NP_009145
- UniProt
- Q9UGP8
- Pathways
- ER-Nucleus Signaling
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