LMAN1 Antikörper

Produktnummer ABIN2462990

Produktdetails anti-LMAN1 Antikörper

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LMAN1.

Anwendungsinformationen

Applikationshinweise: LMAN1 antibody can be used for detection of LMAN1 by ELISA at 1:1562500. LMAN1 antibody can be used for detection of LMAN1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store LMAN1 antibody at -20 °C.

Details zu LMAN1

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Andere Bezeichnung: LMAN1 (LMAN1 Produkte)

Synonyme: ERGIC-53 antikoerper, ERGIC53 antikoerper, F5F8D antikoerper, FMFD1 antikoerper, MCFD1 antikoerper, MR60 antikoerper, gp58 antikoerper, 2610020P13Rik antikoerper, AI326273 antikoerper, AU043785 antikoerper, C730041J05 antikoerper, P58 antikoerper, p58 antikoerper, LMAN1 antikoerper, cpx-iii antikoerper, cpxiii antikoerper, lman1 antikoerper, wu:fc54c09 antikoerper, wu:fi36e01 antikoerper, Xp58 antikoerper, lman1-a antikoerper, lectin, mannose binding 1 antikoerper, lectin, mannose-binding, 1 antikoerper, complexin 3 antikoerper, lectin, mannose binding 1 S homeolog antikoerper, LMAN1 antikoerper, Lman1 antikoerper, cplx3 antikoerper, lman1 antikoerper, lman1.S antikoerper

Hintergrund: LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

Molekulargewicht: 54 kDa

Gen-ID: 3998

NCBI Accession: NP_005561

UniProt: P49257