SWAP70 Antikörper

Produktnummer ABIN2462957

Der Kaninchen Polyklonal Anti-SWAP70-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, SWAP70 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SWAP70 Antikörper (ABIN2462957)

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SWAP70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SWAP70 Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SWAP70.

Anwendungsinformationen

Applikationshinweise: SWAP70 antibody can be used for detection of SWAP70 by ELISA at 1:62500. SWAP70 antibody can be used for detection of SWAP70 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SWAP70 antibody at -20 °C.

Details zu SWAP70

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Andere Bezeichnung: SWAP70

Hintergrund: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

Molekulargewicht: 69 kDa

Gen-ID: 23075

NCBI Accession: NP_055870

UniProt: Q9UH65

Pathways: Production of Molecular Mediator of Immune Response