MTUS1 Antikörper

Produktnummer ABIN2462816

Der Kaninchen Polyklonal anti-MTUS1 Antikörper wird verwendet zum Nachweis von MTUS1 in Proben von Human, Maus und Hund. Er wurde validiert für WB und ELISA.

Kurzübersicht für MTUS1 Antikörper (ABIN2462816)

Target: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Reaktivität: Human, Maus, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTUS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MTUS1 Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MTUS1.

Anwendungsinformationen

Applikationshinweise: MTUS1 antibody can be used for detection of MTUS1 by ELISA at 1:1562500. MTUS1 antibody can be used for detection of MTUS1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MTUS1 antibody at -20 °C.

Details zu MTUS1

Target: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Andere Bezeichnung: MTUS1

Hintergrund: MTUS1 contains a C-terminal domain and is able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. One of the isoforms has been shown to be a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other isoforms may be nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.

Molekulargewicht: 48 kDa, 141 kDa, 136 kDa, 59 kDa

Gen-ID: 57509

NCBI Accession: NP_065800