DTX2 Antikörper

Produktnummer ABIN2462679

Dieses Anti-DTX2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DTX2 in WB und ELISA. Geeignet für Human, Hund und Zebrafisch (Danio rerio).

Kurzübersicht für DTX2 Antikörper (ABIN2462679)

Target: DTX2 (Deltex Homolog 2 (DTX2))

Reaktivität: Human, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DTX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-DTX2 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DTX2.

Anwendungsinformationen

Applikationshinweise: DTX2 antibody can be used for detection of DTX2 by ELISA at 1:312500. DTX2 antibody can be used for detection of DTX2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DTX2 antibody at -20 °C.

Details zu DTX2

Target: DTX2 (Deltex Homolog 2 (DTX2))

Andere Bezeichnung: DTX2

Hintergrund: DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Molekulargewicht: 62 kDa, 67 kDa, 67 kDa, 67 kDa, 93 kDa, 26 kDa, 93 kDa, 45 kDa

Gen-ID: 113878

NCBI Accession: NP_001096066

UniProt: Q6XM87

Pathways: Notch Signalweg