BAG2 Antikörper

Produktnummer ABIN2462540

Produktdetails anti-BAG2 Antikörper

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BAG2.

Anwendungsinformationen

Applikationshinweise: BAG2 antibody can be used for detection of BAG2 by ELISA at 1:1562500. BAG2 antibody can be used for detection of BAG2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store BAG2 antibody at -20 °C.

Details zu BAG2

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Andere Bezeichnung: BAG2 (BAG2 Produkte)

Synonyme: bag2 antikoerper, MGC89300 antikoerper, BAG2 antikoerper, ATBAG2 antikoerper, BCL-2-associated athanogene 2 antikoerper, MTG10.13 antikoerper, MTG10_13 antikoerper, BAG-2 antikoerper, dJ417I1.2 antikoerper, zgc:64195 antikoerper, 2610042A13Rik antikoerper, BC016230 antikoerper, BCL2 associated athanogene 2 antikoerper, BCL-2-associated athanogene 2 antikoerper, BCL2-associated athanogene 2 antikoerper, Bcl2-associated athanogene 2 antikoerper, bag2 antikoerper, BAG2 antikoerper, Bag2 antikoerper

Hintergrund: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Molekulargewicht: 23 kDa

Gen-ID: 9532

NCBI Accession: NP_004273

UniProt: O95816