Keratin 2 Antikörper
Kurzübersicht für Keratin 2 Antikörper (ABIN2462466)
Target
Alle Keratin 2 (KRT2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KRT2A.
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Applikationshinweise
- KRT2A antibody can be used for detection of KRT2A by ELISA at 1:312500. KRT2A antibody can be used for detection of KRT2A by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Konzentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store KRT2A antibody at -20 °C.
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- Keratin 2 (KRT2)
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Andere Bezeichnung
- KRT2A
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Hintergrund
- KRT2A is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
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Molekulargewicht
- 70 kDa
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Gen-ID
- 3849
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NCBI Accession
- NP_000414
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UniProt
- P35908
Target
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