ASL Antikörper

Produktnummer ABIN2462448

Produktdetails anti-ASL Antikörper

Target: ASL (Argininosuccinate Lyase (ASL))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ASL.

Anwendungsinformationen

Applikationshinweise: ASL antibody can be used for detection of ASL by ELISA at 1:62500. ASL antibody can be used for detection of ASL by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ASL antibody at -20 °C.

Details zu ASL

Target: ASL (Argininosuccinate Lyase (ASL))

Andere Bezeichnung: ASL (ASL Produkte)

Synonyme: ASAL antikoerper, 2510006M18Rik antikoerper, zgc:63532 antikoerper, BA4879 antikoerper, PSPTO0125 antikoerper, Adl antikoerper, Asl antikoerper, argininosuccinate lyase antikoerper, argininosuccinate lyase ArgH antikoerper, adenylosuccinate lyase antikoerper, argininosuccinate lyase L homeolog antikoerper, ASL antikoerper, Asl antikoerper, asl antikoerper, argH2 antikoerper, argH antikoerper, arg7 antikoerper, CNC04420 antikoerper, STHERM_c13370 antikoerper, Adsl antikoerper, asl.L antikoerper, ARG7 antikoerper

Hintergrund: ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.

Molekulargewicht: 49 kDa, 52 kDa, 52 kDa, 49 kDa

Gen-ID: 435

NCBI Accession: NP_001020115

UniProt: P04424

Pathways: Response to Growth Hormone Stimulus