GNB1L Antikörper
Kurzübersicht für GNB1L Antikörper (ABIN2462388)
Target
Alle GNB1L Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Antibody is purified by protein A chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GNB1L.
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Applikationshinweise
- GNB1L antibody can be used for detection of GNB1L by ELISA at 1:12500. GNB1L antibody can be used for detection of GNB1L by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Konzentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store GNB1L antibody at -20 °C.
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- GNB1L (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1-Like (GNB1L))
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Andere Bezeichnung
- GNB1L
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Hintergrund
- GNB1L is a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. Therefore, this gene may contribute to the etiology of those disorders.This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders.
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Molekulargewicht
- 36 kDa
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Gen-ID
- 54584
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NCBI Accession
- NP_443730
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UniProt
- Q9BYB4
Target
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