PCBP4 Antikörper

Produktnummer ABIN2462288

Der Kaninchen Polyklonal Anti-PCBP4-Antikörper wurde für ELISA und WB validiert. Er ist geeignet, PCBP4 in Proben von Human, Maus, Ratte und Hund zu detektieren.

Kurzübersicht für PCBP4 Antikörper (ABIN2462288)

Target: PCBP4 (Poly(rC) Binding Protein 4 (PCBP4))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCBP4 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-PCBP4 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCBP4.

Anwendungsinformationen

Applikationshinweise: PCBP4 antibody can be used for detection of PCBP4 by ELISA at 1:62500. PCBP4 antibody can be used for detection of PCBP4 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCBP4 antibody at -20 °C.

Details zu PCBP4

Target: PCBP4 (Poly(rC) Binding Protein 4 (PCBP4))

Andere Bezeichnung: PCBP4

Hintergrund: PCBP4 is a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G (2)-M.This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G (2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.

Molekulargewicht: 47 kDa, 41 kDa, 38 kDa, 41 kDa

Gen-ID: 57060

NCBI Accession: NP_065151

UniProt: Q9GZT1