DAZ2 Antikörper

Produktnummer ABIN2462070

Produktdetails anti-DAZ2 Antikörper

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAZ2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DAZ2.

Anwendungsinformationen

Applikationshinweise: DAZ2 antibody can be used for detection of DAZ2 by ELISA at 1:62500. DAZ2 antibody can be used for detection of DAZ2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DAZ2 antibody at -20 °C.

Details zu DAZ2

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Andere Bezeichnung: DAZ2 (DAZ2 Produkte)

Synonyme: pDP1678 antikoerper, DAZ2 antikoerper, deleted in azoospermia 2 antikoerper, deleted in azoospermia protein 2 antikoerper, DAZ2 antikoerper, LOC738583 antikoerper

Hintergrund: DAZ2 is a member of the DAZ family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). This RNA-binding protein is important for spermatogenesis.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 59 kDa, 65 kDa, 65 kDa, 41 kDa, 65 kDa, 65 kDa, 63 kDa, 50 kDa, 44 kDa

Gen-ID: 57055

NCBI Accession: NP_001005785

UniProt: Q2KHN6