ZNF496 Antikörper

Produktnummer ABIN2461953

Dieses Anti-ZNF496-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ZNF496 in WB und ELISA. Geeignet für Maus, Human und Hund.

Kurzübersicht für ZNF496 Antikörper (ABIN2461953)

Target: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Reaktivität: Maus, Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF496 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ZNF496 Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF496.

Anwendungsinformationen

Applikationshinweise: ZNF496 antibody can be used for detection of ZNF496 by ELISA at 1:62500. ZNF496 antibody can be used for detection of ZNF496 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZNF496 antibody at -20 °C.

Details zu ZNF496

Target: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Andere Bezeichnung: ZNF496

Hintergrund: ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn (II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.

Molekulargewicht: 67 kDa

Gen-ID: 84838

NCBI Accession: NP_116141

UniProt: Q96IT1