ZNF496 Antikörper
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- Target Alle ZNF496 Antikörper anzeigen
- ZNF496 (Zinc Finger Protein 496 (ZNF496))
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Reaktivität
- Maus, Human, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZNF496 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF496.
- Top Product
- Discover our top product ZNF496 Primärantikörper
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- Applikationshinweise
- ZNF496 antibody can be used for detection of ZNF496 by ELISA at 1:62500. ZNF496 antibody can be used for detection of ZNF496 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZNF496 antibody at -20 °C.
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- Target
- ZNF496 (Zinc Finger Protein 496 (ZNF496))
- Andere Bezeichnung
- ZNF496 (ZNF496 Produkte)
- Hintergrund
- ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn (II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
- Molekulargewicht
- 67 kDa
- Gen-ID
- 84838
- NCBI Accession
- NP_116141
- UniProt
- Q96IT1
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