PRDM12 Antikörper

Produktnummer ABIN2461913

Der Kaninchen Polyklonal anti-PRDM12 Antikörper wird verwendet zum Nachweis von PRDM12 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für PRDM12 Antikörper (ABIN2461913)

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PRDM12 Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PRDM12.

Anwendungsinformationen

Applikationshinweise: PRDM12 antibody can be used for detection of PRDM12 by ELISA at 1:62500. PRDM12 antibody can be used for detection of PRDM12 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PRDM12 antibody at -20 °C.

Details zu PRDM12

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Andere Bezeichnung: PRDM12

Hintergrund: PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.

Molekulargewicht: 40 kDa

Gen-ID: 59335

NCBI Accession: NP_067632

UniProt: Q9H4Q4