GATAD2B Antikörper

Produktnummer ABIN2461904

Der Kaninchen Polyklonal anti-GATAD2B Antikörper wird verwendet zum Nachweis von GATAD2B in Proben von Human, Maus, Ratte und Hund. Er wurde validiert für WB und ELISA.

Kurzübersicht für GATAD2B Antikörper (ABIN2461904)

Target: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATAD2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GATAD2B Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GATAD2B.

Anwendungsinformationen

Applikationshinweise: GATAD2B antibody can be used for detection of GATAD2B by ELISA at 1:312500. GATAD2B antibody can be used for detection of GATAD2B by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GATAD2B antibody at -20 °C.

Details zu GATAD2B

Target: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Andere Bezeichnung: GATAD2B

Hintergrund: Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta). Both proteins interact with MBD2 and MBD3 functionally and biochemically. Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa. Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern. These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.

Molekulargewicht: 65 kDa

Gen-ID: 57459

NCBI Accession: NP_065750

UniProt: Q8WXI9