MafF Antikörper

Produktnummer ABIN2461834

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MafF in ELISA und WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio) und Drosophila melanogaster.

Kurzübersicht für MafF Antikörper (ABIN2461834)

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Drosophila melanogaster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MafF Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-MafF Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAFF.

Anwendungsinformationen

Applikationshinweise: MAFF antibody can be used for detection of MAFF by ELISA at 1:62500. MAFF antibody can be used for detection of MAFF by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MAFF antibody at -20 °C.

Details zu MafF

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Andere Bezeichnung: MAFF

Hintergrund: MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene.

Molekulargewicht: 18 kDa, 18 kDa, 18 kDa, 18 kDa, 18 kDa

Gen-ID: 23764

NCBI Accession: NP_690617

UniProt: Q9ULX9

Pathways: Myometrial Relaxation and Contraction