ZNF259 Antikörper

Produktnummer ABIN2461709

Der Kaninchen Polyklonal Anti-ZNF259-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, ZNF259 in Proben von Human, Maus, Ratte und Hund zu detektieren.

Kurzübersicht für ZNF259 Antikörper (ABIN2461709)

Target: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF259 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ZNF259 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF259.

Anwendungsinformationen

Applikationshinweise: ZNF259 antibody can be used for detection of ZNF259 by ELISA at 1:312500. ZNF259 antibody can be used for detection of ZNF259 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZNF259 antibody at -20 °C.

Details zu ZNF259

Target: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Andere Bezeichnung: ZNF259

Hintergrund: ZNF259 may be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. ZNF259 binds to the EGFR and is released from the receptor after activation.ZNF259 is essential for cell viability and its interaction with eEF-1alpha contributes to normal cellular proliferation.ZNF259 translocates from the cytoplasm to the nucleus after treatment of cells with mitogens. ZNF259 accumulates in the nucleolus of proliferating cells. Loss of ZNF259 caused disruption of nucleolar function, including preribosomal RNA expression. ZNF259 is an essential protein that is required for normal nucleolar function in proliferating cells.

Molekulargewicht: 51 kDa

Gen-ID: 8882

NCBI Accession: NP_003895

UniProt: O75312