SAP30 Antikörper
Kurzübersicht für SAP30 Antikörper (ABIN2461708)
Target
Alle SAP30 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
 - Antibody is purified by protein A chromatography method.
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Immunogen
 - Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SAP30.
 
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Applikationshinweise
 - SAP30 antibody can be used for detection of SAP30 by ELISA at 1:312500. SAP30 antibody can be used for detection of SAP30 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Lyophilized
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Rekonstitution
 - Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Konzentration
 - 1 mg/mL
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Buffer
 - Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handhabung
 - As with any antibody avoid repeat freeze-thaw cycles.
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Lagerung
 - 4 °C/-20 °C
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Informationen zur Lagerung
 - For short periods of storage (days) store at 4 °C. For longer periods of storage, store SAP30 antibody at -20 °C.
 
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- SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))
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Andere Bezeichnung
 - SAP30
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Hintergrund
 - Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.
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Molekulargewicht
 - 23 kDa
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Gen-ID
 - 8819
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NCBI Accession
 - NP_003855
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UniProt
 - O75446
 
Target
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