Der Kaninchen Polyklonal anti-TRIM23 Antikörper (ABIN2461638) detektiert spezifisch TRIM23 in WB und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus und Hund.
TRIM23 antibody can be used for detection of TRIM23 by ELISA at 1:62500. TRIM23 antibody can be used for detection of TRIM23 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung
As with any antibody avoid repeat freeze-thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
For short periods of storage (days) store at 4 °C. For longer periods of storage, store TRIM23 antibody at -20 °C.
Target
TRIM23
(Tripartite Motif Containing 23 (TRIM23))
Andere Bezeichnung
TRIM23
Hintergrund
TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.