YAF2 Antikörper

Produktnummer ABIN2461508

Der Kaninchen Polyklonal Anti-YAF2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, YAF2 in Proben von Maus zu detektieren.

Kurzübersicht für YAF2 Antikörper (ABIN2461508)

Target: YAF2 (YY1 Associated Factor 2 (YAF2))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YAF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-YAF2 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse YAF2.

Anwendungsinformationen

Applikationshinweise: YAF2 antibody can be used for detection of YAF2 by ELISA at 1:312500. YAF2 antibody can be used for detection of YAF2 by western blot at 0.2 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store YAF2 antibody at -20 °C.

Details zu YAF2

Target: YAF2 (YY1 Associated Factor 2 (YAF2))

Andere Bezeichnung: YAF2

Hintergrund: Yaf2 binds to MYC and inhibits MYC-mediated transactivation. Yaf2 also binds to MYCN and enhances MYCN-dependent transcriptional activation. Yaf2 increases calpain 2-mediated proteolysis of YY1 in vitro. Yaf2 is a component of the E2F6.com-1 complex, a repressive complex that methylates Lys-9 of histone H3, suggesting that it is involved in chromatin-remodeling.

Molekulargewicht: 20 kDa

Gen-ID: 67057

NCBI Accession: NP_077151

UniProt: Q99LW6