MIER1 Antikörper

Produktnummer ABIN2460961

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MIER1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund und Zebrafisch (Danio rerio).

Kurzübersicht für MIER1 Antikörper (ABIN2460961)

Target: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIER1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MIER1 Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MIER1.

Anwendungsinformationen

Applikationshinweise: MIER1 antibody can be used for detection of MIER1 by ELISA at 1:312500. MIER1 antibody can be used for detection of MIER1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MIER1 antibody at -20 °C.

Details zu MIER1

Target: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Andere Bezeichnung: MIER1

Hintergrund: The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).

Molekulargewicht: 49 kDa

Gen-ID: 57708

NCBI Accession: NP_065999

UniProt: Q8NES5

Pathways: Chromatin Binding