MED17 Antikörper

Produktnummer ABIN2460890

Der Kaninchen Polyklonal Anti-MED17-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, MED17 in Proben von Human, Ratte und Hund zu detektieren.

Kurzübersicht für MED17 Antikörper (ABIN2460890)

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Reaktivität: Human, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-MED17 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CRSP6.

Anwendungsinformationen

Applikationshinweise: CRSP6 antibody can be used for detection of CRSP6 by ELISA at 1:12500. CRSP6 antibody can be used for detection of CRSP6 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CRSP6 antibody at -20 °C.

Details zu MED17

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Andere Bezeichnung: CRSP6

Hintergrund: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Molekulargewicht: 73 kDa

Gen-ID: 9440

NCBI Accession: NP_004259

UniProt: Q9NVC6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha